Read the crowd.
Learn to club with your clubbers. If they are clapping, jumping, dancing their butts off and packing the floor then keep it moving. if you feel like they are not responding well, or you have allot of wall flowers, try and change it up a bit, see what gets the most reaction out of them. once you find that key point, then let em have it.
And dont feel like you have to just sit there and spin all night. Show them you are into it as well. Look at them, smile, jump, get into it. After a two hour set i am exhausted, but i know i have connected with everyone on that dance floor. if they feel a connection with you, there will be an energy like no other.